diff --git a/colossalai/cli/__init__.py b/colossalai/cli/__init__.py
new file mode 100644
index 000000000..e69de29bb
diff --git a/colossalai/cli/cli.py b/colossalai/cli/cli.py
new file mode 100644
index 000000000..ee04572fa
--- /dev/null
+++ b/colossalai/cli/cli.py
@@ -0,0 +1,54 @@
+import click
+from colossalai.cli.launcher.run import main as col_launch
+
+class Arguments():
+    def __init__(self, dict):
+        for k, v in dict.items():
+            self.__dict__[k] = v
+
+@click.group()
+def cli():
+    pass
+
+@click.command()
+@click.option("--hostfile", 
+                type=str,
+                default="")
+@click.option("--include",
+              type=str,
+              default="")
+@click.option("--exclude",
+                type=str,
+                default="")
+@click.option("--num_nodes",
+                type=int,
+                default=-1)
+@click.option("--num_gpus",
+                type=int,
+                default=-1)
+@click.option("--master_port",
+                type=int,
+                default=29500)
+@click.option("--master_addr",
+                type=str,
+                default="127.0.0.1")
+@click.option("--launcher",
+                type=str,
+                default="torch")
+@click.option("--launcher_args",
+                type=str,
+                default="")
+@click.argument("user_script",
+                type=str)
+@click.argument('user_args', nargs=-1)
+def launch(hostfile, num_nodes, num_gpus, include, exclude, master_addr, master_port, 
+           launcher, launcher_args, user_script, user_args):
+    args_dict = locals()
+    args = Arguments(args_dict)
+    args.user_args = list(args.user_args)
+    col_launch(args)
+
+cli.add_command(launch)
+
+if __name__ == '__main__':
+    cli()
diff --git a/colossalai/cli/launcher/__init__.py b/colossalai/cli/launcher/__init__.py
new file mode 100644
index 000000000..e69de29bb
diff --git a/colossalai/cli/launcher/multinode_runner.py b/colossalai/cli/launcher/multinode_runner.py
new file mode 100644
index 000000000..ecdeb317b
--- /dev/null
+++ b/colossalai/cli/launcher/multinode_runner.py
@@ -0,0 +1,146 @@
+import os
+import sys
+import shutil
+import subprocess
+import warnings
+from shlex import quote
+from abc import ABC, abstractmethod
+
+from colossalai.logging import get_dist_logger
+
+logger = get_dist_logger()
+
+class MultiNodeRunner(ABC):
+    def __init__(self, args):
+        self.args = args
+        self.user_arguments = self.args.user_args
+        self.user_script = args.user_script
+        self.exports = {}
+
+    @abstractmethod
+    def backend_exists(self):
+        """Return whether the corresponding backend exists"""
+
+    @abstractmethod
+    def get_cmd(self, environment, active_devices):
+        """Return the command to execute on node"""
+
+    def add_export(self, key, var):
+        self.exports[key.strip()] = var.strip()
+
+    @property
+    def name(self):
+        """Return the name of the backend"""
+        return self.__class__.__name__
+
+
+class PDSHRunner(MultiNodeRunner):
+    def __init__(self, args):
+        super().__init__(args)
+
+    def backend_exists(self):
+        return shutil.which('pdsh')
+
+    @property
+    def name(self):
+        return "pdsh"
+
+    def parse_user_args(self):
+        return list(
+            map(lambda x: x if x.startswith("-") else f"'{x}'",
+                self.args.user_args))
+
+    def get_cmd(self, environment, active_devices, args):
+        environment['PDSH_RCMD_TYPE'] = 'ssh'
+
+        active_workers = ",".join(active_devices.keys())
+        logger.info("Running on the following workers: %s" % active_workers)
+
+        pdsh_cmd_args = ['pdsh', '-f', str(1024), '-w', active_workers]
+
+        exports = ""
+        for key, val in self.exports.items():
+            exports += f"export {key}={quote(val)}; "
+
+        # https://linux.die.net/man/1/pdsh
+        # %n will be replaced by pdsh command
+        colossal_launch = [
+            exports,
+            f"cd {os.path.abspath('.')};",
+            sys.executable, "-u", "-m", 
+            "torch.distributed.launch",
+            f"--nproc_per_node={args.num_gpus}",
+            f"--master_addr={args.master_addr}",
+            f"--master_port={args.master_port}"
+        ]
+        return pdsh_cmd_args + colossal_launch + [self.user_script] + self.user_arguments
+
+class OpenMPIRunner(MultiNodeRunner):
+    def __init__(self, args, device_pool):
+        super().__init__(args)
+        self.device_pool = device_pool
+
+    def backend_exists(self):
+        return shutil.which('ompi_info')
+
+    @property
+    def name(self):
+        return "openmpi"
+
+    def get_cmd(self, environment, active_devices):
+        total_process_count = sum(self.device_pool.values())
+
+        mpirun_cmd = [
+            'mpirun',
+            '-n',
+            f'{total_process_count}',
+            '-hostfile',
+            f'{self.args.hostfile}'
+        ]
+
+        export_cmd = []
+        for k, v in self.exports.items():
+            export_cmd += ['-x', f'{k}={quote(v)}']
+
+        python_exec = []
+        python_exec = [sys.executable, "-u", "-m"]
+
+        return mpirun_cmd + export_cmd + python_exec + [self.user_script
+                                                        ] + self.user_arguments
+
+class SLURMRunner(MultiNodeRunner):
+    def __init__(self, args):
+        super().__init__(args)
+
+    def backend_exists(self):
+        return shutil.which('slurm_info')
+
+    @property
+    def name(self):
+        return "slurm"
+
+    def get_cmd(self, environment, active_devices, args):
+
+        assert "-p" in args.launcher_args
+        srun_args = args.launcher_args.strip().split()
+        assert len(srun_args) >= 2, "we need more info about which partition to use."
+        partition_name = srun_args(srun_args.index("-p")+1)
+        slurm_cmd = [
+            'srun',
+            "-p",
+            f"{partition_name}",
+            "--nodes",
+            f"{args.num_nodes}",
+            "--tasks",
+            f"{args.num_gpus}"
+        ]
+
+        export_cmd = []
+        for k, v in self.exports.items():
+            export_cmd += ['-x', f'{k}={quote(v)}']
+
+        python_exec = []
+        python_exec = [sys.executable, "-u", "-m"]
+
+        return slurm_cmd + export_cmd + python_exec + [self.user_script
+                                                        ] + self.user_arguments
diff --git a/colossalai/cli/launcher/run.py b/colossalai/cli/launcher/run.py
new file mode 100644
index 000000000..8097f1b56
--- /dev/null
+++ b/colossalai/cli/launcher/run.py
@@ -0,0 +1,285 @@
+import argparse
+from argparse import ArgumentParser, REMAINDER
+import subprocess
+import collections
+import sys
+import os
+import torch
+from colossalai.logging import get_dist_logger
+from .multinode_runner import PDSHRunner, OpenMPIRunner, SLURMRunner
+
+def build_args_parser() -> ArgumentParser:
+    """Helper function parsing the command line options."""
+
+    parser = ArgumentParser(description="colossal distributed training launcher")
+
+    parser.add_argument("-H",
+                        "--hostfile",
+                        type=str,
+                        default="",
+                        help="Hostfile path that defines the "
+                        "device pool available to the job (e.g., "
+                        "worker-name:number of slots)")
+
+    parser.add_argument("-i",
+                        "--include",
+                        type=str,
+                        default="",
+                        help="Specify computing devices to use during execution."
+                        "String format is NODE_SPEC@NODE_SPEC"
+                        "where NODE_SPEC=<worker-name>:<list-of-slots>")
+
+    parser.add_argument("-e",
+                        "--exclude",
+                        type=str,
+                        default="",
+                        help="Specify computing devices to NOT use during execution."
+                        "Mutually exclusive with --include. Formatting"
+                        "is the same as --include.")
+
+    parser.add_argument("--num_nodes",
+                        type=int,
+                        default=-1,
+                        help="Total number of worker nodes to use.")
+
+    parser.add_argument("--num_gpus",
+                        type=int,
+                        default=-1,
+                        help="Number of GPUs to use on each node.")
+
+    parser.add_argument("--master_port",
+                        default=29500,
+                        type=int,
+                        help="(optional) Port used by PyTorch distributed for "
+                        "communication during distributed training.")
+
+    parser.add_argument("--master_addr",
+                        default="127.0.0.1",
+                        type=str,
+                        help="(optional) IP address of node 0, will be "
+                        "inferred via 'hostname -I' if not specified.")
+
+    parser.add_argument("--launcher",
+                        default="torch",
+                        type=str,
+                        help="(optional) choose launcher backend for multi-node "
+                        "training. Options currently include PDSH, OpenMPI, SLURM.")
+
+    parser.add_argument("--launcher_args",
+                        default="",
+                        type=str,
+                        help="(optional) pass launcher specific arguments as a "
+                        "single quoted argument.")
+
+    parser.add_argument("user_script",
+                        type=str,
+                        help="User script to launch, followed by any required "
+                        "arguments.")
+    
+    parser.add_argument('user_args', nargs=argparse.REMAINDER)
+
+    return parser
+
+def fetch_hostfile(hostfile_path):
+    logger = get_dist_logger()
+    if not os.path.isfile(hostfile_path):
+        logger.warning("Unable to find hostfile, will proceed with training "
+                       "with local resources only")
+        return None
+
+    # e.g., worker-0:16
+    with open(hostfile_path, 'r') as fd:
+        device_pool = collections.OrderedDict()
+        for line in fd.readlines():
+            line = line.strip()
+            if line == '':
+                # skip empty lines
+                continue
+            try:
+                hostname, slot_count = line.split(":")
+                slot_count = int(slot_count)
+            except ValueError as err:
+                logger.error("Hostfile is not formatted correctly, unable to "
+                             "proceed with training.")
+                raise err
+            device_pool[hostname] = slot_count
+
+    return device_pool
+
+def _stable_remove_duplicates(data):
+    # Create a new list in the same order as original but with duplicates
+    # removed, should never be more than ~16 elements so simple is best
+    new_list = []
+    for x in data:
+        if x not in new_list:
+            new_list.append(x)
+    return new_list
+
+def parse_device_filter(host_info, include_str="", exclude_str=""):
+    '''Parse an inclusion or exclusion string and filter a hostfile dictionary.
+
+    Examples:
+        include_str="worker-0@worker-1:0,2" will use all slots on worker-0 and
+          slots [0, 2] on worker-1.
+        exclude_str="worker-1:0" will use all available devices except
+          slot 0 on worker-1.
+    '''
+
+    logger = get_dist_logger()
+
+    # Constants that define our syntax
+    NODE_SEP = '@'
+    SLOT_LIST_START = ':'
+    SLOT_SEP = ','
+
+    # Ensure include/exclude are mutually exclusive
+    if (include_str != "") and (exclude_str != ""):
+        raise ValueError('include_str and exclude_str are mutually exclusive.')
+
+    # no-op
+    if (include_str == "") and (exclude_str == ""):
+        return host_info
+
+    # Either build from scratch or remove items
+    filtered_hosts = dict()
+    if include_str:
+        parse_str = include_str
+    if exclude_str != "":
+        filtered_hosts = deepcopy(host_info)
+        parse_str = exclude_str
+
+    # foreach node in the list
+    for node_config in parse_str.split(NODE_SEP):
+        # Node can either be alone or node:slot,slot,slot
+        if SLOT_LIST_START in node_config:
+            hostname, slots = node_config.split(SLOT_LIST_START)
+            slots = [int(x) for x in slots.split(SLOT_SEP)]
+
+            # sanity checks
+            if hostname not in host_info:
+                raise ValueError(f"Hostname '{hostname}' not found in hostfile")
+            for slot in slots:
+                if slot not in host_info[hostname]:
+                    raise ValueError(f"No slot '{slot}' specified on host '{hostname}'")
+
+            # If include string, build the list from here
+            if include_str:
+                filtered_hosts[hostname] = slots
+            elif exclude_str:
+                for slot in slots:
+                    logger.info(f'removing {slot} from {hostname}')
+                    filtered_hosts[hostname].remove(slot)
+
+        # User just specified the whole node
+        else:
+            hostname = node_config
+            # sanity check hostname
+            if hostname not in host_info:
+                raise ValueError(f"Hostname '{hostname}' not found in hostfile")
+
+            if include_str:
+                filtered_hosts[hostname] = host_info[hostname]
+            elif exclude_str:
+                filtered_hosts[hostname] = []
+
+    # Post-processing to remove duplicates and empty nodes
+    del_keys = []
+    for hostname in filtered_hosts:
+        # Remove duplicates
+        filtered_hosts[hostname] = _stable_remove_duplicates(filtered_hosts[hostname])
+        # Remove empty hosts
+        if len(filtered_hosts[hostname]) == 0:
+            del_keys.append(hostname)
+    for name in del_keys:
+        del filtered_hosts[name]
+
+    # Lastly, go over filtered_hosts and convert to a OrderedDict() to ensure
+    # we map ranks to nodes correctly by maintaining host_info ordering.
+    ordered_hosts = collections.OrderedDict()
+    for host in host_info:
+        if host in filtered_hosts:
+            ordered_hosts[host] = filtered_hosts[host]
+
+    return ordered_hosts
+
+def parse_inclusion_exclusion(device_pool, inclusion, exclusion):
+    active_devices = collections.OrderedDict()
+    for hostname, slots in device_pool.items():
+        active_devices[hostname] = list(range(slots))
+
+    return parse_device_filter(active_devices,
+                                 include_str=inclusion,
+                                 exclude_str=exclusion)
+
+def main(args=None):
+    logger = get_dist_logger()
+    assert args is not None, "args should not be None."
+    
+    device_pool = fetch_hostfile(args.hostfile)
+
+    active_devices = None
+    if device_pool:
+        active_devices = parse_inclusion_exclusion(device_pool,
+                                                 args.include,
+                                                 args.exclude)
+        if args.num_nodes > 0:
+            updated_active_devices = collections.OrderedDict()
+            for count, hostname in enumerate(active_devices.keys()):
+                if args.num_nodes == count:
+                    break
+                updated_active_devices[hostname] = active_devices[hostname]
+            active_devices = updated_active_devices
+
+        if args.num_gpus > 0:
+            updated_active_devices = collections.OrderedDict()
+            for hostname in active_devices.keys():
+                updated_active_devices[hostname] = list(range(args.num_gpus))
+            active_devices = updated_active_devices
+
+    env = os.environ.copy()
+
+    if not active_devices:
+        if args.num_gpus == -1 or args.num_gpus > torch.cuda.device_count():
+            nproc_per_node = torch.cuda.device_count()
+        else:
+            nproc_per_node = args.num_gpus
+        if torch.__version__ <= "1.09":
+            cmd = [sys.executable, "-u", "-m", 
+                    "torch.distributed.launch",
+                    f"--nproc_per_node={nproc_per_node}",
+                    f"--master_addr={args.master_addr}",
+                    f"--master_port={args.master_port}"] + [args.user_script] + args.user_args
+        else:
+            cmd = ["torchrun",
+                    f"--nproc_per_node={nproc_per_node}",
+                    f"--master_addr={args.master_addr}",
+                    f"--master_port={args.master_port}"] + [args.user_script] + args.user_args
+    else:
+        if args.launcher == "torch":
+            runner = PDSHRunner(args)
+        elif args.launcher == "mpi":
+            runner = OpenMPIRunner(args, device_pool)
+        elif args.launcher == "slurm":
+            runner = SLURMRunner(args, device_pool)
+        else:
+            raise NotImplementedError(f"Unknown launcher {args.launcher}")
+
+        if not runner.backend_exists():
+            raise RuntimeError(f"launcher '{args.launcher}' not installed.")
+
+        curr_path = os.path.abspath('.')
+        if 'PYTHONPATH' in env:
+            env['PYTHONPATH'] = curr_path + ":" + env['PYTHONPATH']
+        else:
+            env['PYTHONPATH'] = curr_path
+        
+        cmd = runner.get_cmd(env, active_devices, args)
+    
+    result = subprocess.Popen(cmd, env=env)
+    result.wait()
+    if result.returncode > 0:
+        sys.exit(result.returncode)
+
+
+if __name__ == "__main__":
+    main()
diff --git a/setup.py b/setup.py
index ec281e2e9..98d3d3e00 100644
--- a/setup.py
+++ b/setup.py
@@ -213,6 +213,10 @@ setup(
     ext_modules=ext_modules,
     cmdclass={'build_ext': BuildExtension} if ext_modules else {},
     install_requires=fetch_requirements('requirements/requirements.txt'),
+    entry_points='''
+        [console_scripts]
+        colossal=colossalai.cli.cli:cli
+    ''',
     python_requires='>=3.7',
     classifiers=[
         'Programming Language :: Python :: 3',