diff --git a/misc/config_tools/acpi_gen/asl_gen.py b/misc/config_tools/acpi_gen/asl_gen.py
index 2f017ff15..c06ef5423 100644
--- a/misc/config_tools/acpi_gen/asl_gen.py
+++ b/misc/config_tools/acpi_gen/asl_gen.py
@@ -9,7 +9,7 @@ import sys, os, re, argparse, shutil, ctypes
 from acpi_const import *
 import board_cfg_lib, acrn_config_utilities
 import collections
-import lxml.etree
+from defusedxml.lxml import parse
 from acrn_config_utilities import get_node
 
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'board_inspector'))
@@ -861,11 +861,11 @@ def main(args):
     scenario= params['--scenario']
     out = params['--out']
 
-    board_etree = lxml.etree.parse(board)
+    board_etree = parse(board)
     board_root = board_etree.getroot()
-    scenario_etree = lxml.etree.parse(scenario)
+    scenario_etree = parse(scenario)
     scenario_root = scenario_etree.getroot()
-    allocation_etree = lxml.etree.parse(os.path.join(os.path.dirname(board), "configs", "allocation.xml"))
+    allocation_etree = parse(os.path.join(os.path.dirname(board), "configs", "allocation.xml"))
     board_type = board_root.attrib['board']
     scenario_name = scenario_root.attrib['scenario']
     pcpu_list = board_root.find('CPU_PROCESSOR_INFO').text.strip().split(',')
diff --git a/misc/config_tools/acpi_gen/bin_gen.py b/misc/config_tools/acpi_gen/bin_gen.py
index 45056a9b7..217c80abd 100644
--- a/misc/config_tools/acpi_gen/bin_gen.py
+++ b/misc/config_tools/acpi_gen/bin_gen.py
@@ -9,7 +9,7 @@ import logging
 import subprocess # nosec
 import os, sys, argparse, re, shutil
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'board_inspector'))
-import lxml.etree
+from defusedxml.lxml import parse
 from acpi_const import *
 import acpiparser.tpm2
 import inspectorlib.cdata
@@ -251,8 +251,8 @@ def check_iasl(iasl_path, iasl_min_ver):
 
 def main(args):
 
-    board_etree = lxml.etree.parse(args.board)
-    scenario_etree = lxml.etree.parse(args.scenario)
+    board_etree = parse(args.board)
+    scenario_etree = parse(args.scenario)
 
     scenario_name = get_node("//@scenario", scenario_etree)
 
@@ -266,7 +266,7 @@ def main(args):
         hypervisor_out = args.out
     DEST_ACPI_BIN_PATH = os.path.join(hypervisor_out, 'acpi')
 
-    allocation_etree = lxml.etree.parse(os.path.join(hypervisor_out, 'configs', 'allocation.xml'))
+    allocation_etree = parse(os.path.join(hypervisor_out, 'configs', 'allocation.xml'))
 
     if os.path.isdir(DEST_ACPI_BIN_PATH):
         shutil.rmtree(DEST_ACPI_BIN_PATH)
diff --git a/misc/config_tools/board_config/board_c.py b/misc/config_tools/board_config/board_c.py
index c0cfe631f..1971256b8 100644
--- a/misc/config_tools/board_config/board_c.py
+++ b/misc/config_tools/board_config/board_c.py
@@ -7,7 +7,7 @@ import sys
 import enum
 import board_cfg_lib
 import acrn_config_utilities
-import lxml.etree
+from defusedxml.lxml import parse
 import os
 from acrn_config_utilities import get_node
 
@@ -125,7 +125,7 @@ def populate_mba_delay_mask(rdt_res, mba_delay_list, config):
         idx += 1
 
 def get_rdt_enabled():
-    scenario_etree = lxml.etree.parse(acrn_config_utilities.SCENARIO_INFO_FILE)
+    scenario_etree = parse(acrn_config_utilities.SCENARIO_INFO_FILE)
     enable = scenario_etree.xpath(f"//RDT_ENABLED/text()")
     if enable[0] == "y":
         return "true"
@@ -133,7 +133,7 @@ def get_rdt_enabled():
         return "false"
 
 def get_cdp_enabled():
-    scenario_etree = lxml.etree.parse(acrn_config_utilities.SCENARIO_INFO_FILE)
+    scenario_etree = parse(acrn_config_utilities.SCENARIO_INFO_FILE)
     enable = scenario_etree.xpath(f"//CDP_ENABLED/text()")
     if enable[0] == "y":
         return "true"
@@ -154,7 +154,7 @@ def gen_rdt_str(cache, config):
     err_dic = {}
     cat_mask_list = {}
 
-    board_etree = lxml.etree.parse(acrn_config_utilities.BOARD_INFO_FILE)
+    board_etree = parse(acrn_config_utilities.BOARD_INFO_FILE)
     mask_length = get_node(f"./capability[@id='CAT']/capacity_mask_length/text()", cache)
     clos_number = get_node(f"./capability[@id='CAT']/clos_number/text()", cache)
 
@@ -220,7 +220,7 @@ def gen_rdt_str(cache, config):
 
 def get_mask_list(cache_level, cache_id):
     allocation_dir = os.path.split(acrn_config_utilities.SCENARIO_INFO_FILE)[0] + "/configs/allocation.xml"
-    allocation_etree = lxml.etree.parse(allocation_dir)
+    allocation_etree = parse(allocation_dir)
     if cache_level == "3":
         clos_list = allocation_etree.xpath(f"//clos_mask[@id = 'l3']/clos/text()")
     else:
@@ -285,9 +285,9 @@ def gen_rdt_res(config):
     err_dic = {}
     res_present = [0, 0, 0]
 
-    scenario_etree = lxml.etree.parse(acrn_config_utilities.SCENARIO_INFO_FILE)
-    allocation_etree = lxml.etree.parse(acrn_config_utilities.SCENARIO_INFO_FILE)
-    board_etree = lxml.etree.parse(acrn_config_utilities.BOARD_INFO_FILE)
+    scenario_etree = parse(acrn_config_utilities.SCENARIO_INFO_FILE)
+    allocation_etree = parse(acrn_config_utilities.SCENARIO_INFO_FILE)
+    board_etree = parse(acrn_config_utilities.BOARD_INFO_FILE)
 
     cache_list = board_etree.xpath(f"//cache[capability/@id = 'CAT' or capability/@id = 'MBA']")
     gen_clos_array(cache_list, config)
@@ -410,7 +410,7 @@ def gen_px_cx(config):
 def gen_pci_hide(config):
     """Generate hide pci information for this platform"""
 
-    scenario_etree = lxml.etree.parse(acrn_config_utilities.SCENARIO_INFO_FILE)
+    scenario_etree = parse(acrn_config_utilities.SCENARIO_INFO_FILE)
     hidden_pdev_list = [x.replace('.', ':') for x in scenario_etree.xpath(f"//HIDDEN_PDEV/text()")]
 
     if board_cfg_lib.BOARD_NAME in list(board_cfg_lib.KNOWN_HIDDEN_PDEVS_BOARD_DB.keys()) and board_cfg_lib.KNOWN_HIDDEN_PDEVS_BOARD_DB[board_cfg_lib.BOARD_NAME] != 0:
@@ -458,7 +458,7 @@ def gen_known_caps_pci_devs(config):
 
 def gen_cpufreq_limits(config):
     allocation_dir = os.path.split(acrn_config_utilities.SCENARIO_INFO_FILE)[0] + "/configs/allocation.xml"
-    allocation_etree = lxml.etree.parse(allocation_dir)
+    allocation_etree = parse(allocation_dir)
     cpu_list = board_cfg_lib.get_processor_info()
     max_cpu_num = len(cpu_list)
 
diff --git a/misc/config_tools/board_inspector/board_inspector.py b/misc/config_tools/board_inspector/board_inspector.py
index 050717641..0ebe8735c 100755
--- a/misc/config_tools/board_inspector/board_inspector.py
+++ b/misc/config_tools/board_inspector/board_inspector.py
@@ -11,6 +11,7 @@ import logging
 import tempfile
 import subprocess # nosec
 import lxml.etree
+from defusedxml.lxml import parse
 import argparse
 from tqdm import tqdm
 from collections import namedtuple
@@ -158,7 +159,7 @@ def main(board_name, board_xml, args):
             env = { "PYTHONPATH": script_dir, "PATH": os.environ["PATH"] }
             subprocess.run([sys.executable, legacy_parser, args.board_name, "--out", board_xml], check=True, env=env)
             # ... then load the created board XML and append it with additional data by invoking the extractors.
-            board_etree = lxml.etree.parse(board_xml)
+            board_etree = parse(board_xml)
             root_node = board_etree.getroot()
 
             # Clear the whitespaces between adjacent children under the root node
diff --git a/misc/config_tools/board_inspector/inspectorlib/mmio.py b/misc/config_tools/board_inspector/inspectorlib/mmio.py
index eecdd6810..a2a9e5af6 100644
--- a/misc/config_tools/board_inspector/inspectorlib/mmio.py
+++ b/misc/config_tools/board_inspector/inspectorlib/mmio.py
@@ -1,7 +1,7 @@
 #!/usr/bin/env python3
 
 import argparse
-import lxml.etree
+from defusedxml.lxml import parse
 
 def mmio_regions(etree):
     ret = []
@@ -21,7 +21,7 @@ if __name__ == "__main__":
     parser.add_argument("file", help="board XML file")
     args = parser.parse_args()
 
-    etree = lxml.etree.parse(args.file)
+    etree = parse(args.file)
     regions = mmio_regions(etree)
     for region in regions:
         print("%-4s 0x%08x 0x%08x" % (region[0], region[1], region[2]))
diff --git a/misc/config_tools/board_inspector/inspectorlib/validator.py b/misc/config_tools/board_inspector/inspectorlib/validator.py
index 6409fe328..934714f56 100644
--- a/misc/config_tools/board_inspector/inspectorlib/validator.py
+++ b/misc/config_tools/board_inspector/inspectorlib/validator.py
@@ -7,7 +7,7 @@
 
 import sys, os
 import argparse
-import lxml.etree as etree
+from defusedxml.lxml import parse
 import logging
 import xmlschema
 
@@ -18,7 +18,7 @@ logging_fn = {
 }
 
 def validate_board(xsd_path, board_etree):
-    schema_etree = etree.parse(xsd_path)
+    schema_etree = parse(xsd_path)
     schema_etree.xinclude()
     schema = xmlschema.XMLSchema11(schema_etree)
 
diff --git a/misc/config_tools/configurator/pyodide/loadBoard.py b/misc/config_tools/configurator/pyodide/loadBoard.py
index 6917bf652..89d32f79b 100644
--- a/misc/config_tools/configurator/pyodide/loadBoard.py
+++ b/misc/config_tools/configurator/pyodide/loadBoard.py
@@ -8,7 +8,7 @@ import os
 from copy import deepcopy
 
 import elementpath
-import lxml.etree as etree
+from defusedxml.lxml import fromstring
 from bs4 import BeautifulSoup
 
 from . import convert_result, nuc11_board, scenario_json_schema, nuc11_board_path
@@ -20,7 +20,7 @@ def get_dynamic_scenario(board):
     :type board: str
     :param board: board xml text
     """
-    board_xml = etree.fromstring(board)
+    board_xml = fromstring(board)
 
     def get_enum(source, options, option_names, obj_type):
         elements = [str(x) for x in elementpath.select(source, options) if x]
diff --git a/misc/config_tools/configurator/pyodide/populateDefaultValues.py b/misc/config_tools/configurator/pyodide/populateDefaultValues.py
index 241a8263d..dfbed3f74 100644
--- a/misc/config_tools/configurator/pyodide/populateDefaultValues.py
+++ b/misc/config_tools/configurator/pyodide/populateDefaultValues.py
@@ -9,7 +9,7 @@ __package__ = 'configurator.pyodide'
 
 from pathlib import Path
 from tempfile import TemporaryDirectory
-from xml.etree.ElementTree import tostring
+from defusedxml.ElementTree import tostring
 
 from scenario_config.pipeline import PipelineObject, PipelineEngine
 from scenario_config.xml_loader import XMLLoadStage
diff --git a/misc/config_tools/configurator/pyodide/updateSchema.py b/misc/config_tools/configurator/pyodide/updateSchema.py
index 4098d3fc2..2a85b74a3 100644
--- a/misc/config_tools/configurator/pyodide/updateSchema.py
+++ b/misc/config_tools/configurator/pyodide/updateSchema.py
@@ -5,13 +5,14 @@ from .pyodide import convert_result, nuc11_board, nuc11_scenario
 
 import re
 from lxml import etree
+from defusedxml.lxml import fromstring
 
 
 class GenerateSchema:
 
     def __init__(self, board, scenario):
         parser = etree.XMLParser(remove_blank_text=True)
-        self.board_etree = etree.fromstring(board, parser)
+        self.board_etree = fromstring(board, parser)
         self.scenario = scenario
 
     @property
diff --git a/misc/config_tools/launch_config/launch_cfg_gen.py b/misc/config_tools/launch_config/launch_cfg_gen.py
index 88c43d948..3069de47b 100755
--- a/misc/config_tools/launch_config/launch_cfg_gen.py
+++ b/misc/config_tools/launch_config/launch_cfg_gen.py
@@ -16,7 +16,7 @@ import argparse
 
 import logging
 
-import lxml.etree as etree
+from defusedxml.lxml import parse
 
 
 def eval_xpath(element, xpath, default_value=None):
@@ -428,8 +428,8 @@ def generate_for_one_vm(board_etree, hv_scenario_etree, vm_scenario_etree, vm_id
 
 
 def main(board_xml, scenario_xml, user_vm_id, out_dir):
-    board_etree = etree.parse(board_xml)
-    scenario_etree = etree.parse(scenario_xml)
+    board_etree = parse(board_xml)
+    scenario_etree = parse(scenario_xml)
 
     service_vm_id = eval_xpath(scenario_etree, "//vm[load_order = 'SERVICE_VM']/@id")
     service_vm_name = eval_xpath(scenario_etree, "//vm[load_order = 'SERVICE_VM']/name/text()")
diff --git a/misc/config_tools/library/launch_cfg_lib.py b/misc/config_tools/library/launch_cfg_lib.py
index e396b5eb5..2392548d4 100644
--- a/misc/config_tools/library/launch_cfg_lib.py
+++ b/misc/config_tools/library/launch_cfg_lib.py
@@ -11,7 +11,7 @@ import acrn_config_utilities
 import board_cfg_lib
 import scenario_cfg_lib
 import lxml
-import lxml.etree
+from defusedxml.lxml import parse
 
 ERR_LIST = {}
 BOOT_TYPE = ['no', 'ovmf']
@@ -673,7 +673,7 @@ def check_communication_vuart(launch_communication_vuarts, scenario_info):
                 return
 
 def check_enable_ptm(launch_enable_ptm, scenario_info):
-    scenario_etree = lxml.etree.parse(scenario_info)
+    scenario_etree = parse(scenario_info)
     enable_ptm_vm_list = scenario_etree.xpath("//vm[PTM = 'y']/@id")
     for user_vmid, enable_ptm in launch_enable_ptm.items():
         key = 'user_vm:id={},enable_ptm'.format(user_vmid)
diff --git a/misc/config_tools/scenario_config/config_summary.py b/misc/config_tools/scenario_config/config_summary.py
index 7c5619dc2..1a36ba49a 100644
--- a/misc/config_tools/scenario_config/config_summary.py
+++ b/misc/config_tools/scenario_config/config_summary.py
@@ -10,7 +10,7 @@ import logging
 import typing
 import functools
 import textwrap
-from lxml import etree
+from defusedxml.lxml import parse
 
 t_content = typing.Union[str, typing.List[str]]
 
@@ -100,8 +100,8 @@ class GenerateRst:
 
     # Class initialization
     def __init__(self, board_file_name, scenario_file_name, rst_file_name) -> None:
-        self.board_etree = etree.parse(board_file_name)
-        self.scenario_etree = etree.parse(scenario_file_name)
+        self.board_etree = parse(board_file_name)
+        self.scenario_etree = parse(scenario_file_name)
         self.file = open(rst_file_name, 'w')
         self.doc = Doc(self.file)
 
diff --git a/misc/config_tools/scenario_config/lxml_loader.py b/misc/config_tools/scenario_config/lxml_loader.py
index 5d151dbde..557150942 100644
--- a/misc/config_tools/scenario_config/lxml_loader.py
+++ b/misc/config_tools/scenario_config/lxml_loader.py
@@ -5,7 +5,8 @@
 # SPDX-License-Identifier: BSD-3-Clause
 #
 
-from lxml.etree import parse, XMLParser
+from lxml.etree import XMLParser
+from defusedxml.lxml import parse
 from pipeline import PipelineStage
 
 class LXMLLoadStage(PipelineStage):
diff --git a/misc/config_tools/scenario_config/scenario_cfg_gen.py b/misc/config_tools/scenario_config/scenario_cfg_gen.py
index ff47fb288..43d7f7224 100755
--- a/misc/config_tools/scenario_config/scenario_cfg_gen.py
+++ b/misc/config_tools/scenario_config/scenario_cfg_gen.py
@@ -6,7 +6,7 @@
 import os
 import sys
 import copy
-import lxml.etree as etree
+from defusedxml.lxml import parse, tostring
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'library'))
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'hv_config'))
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'acpi_gen'))
@@ -100,9 +100,9 @@ def validate_scenario_schema(scenario_info):
     XMLSchema does not process XInclude.
     Use lxml to expand the schema which is feed to XMLSchema as a string.
     """
-    xsd_doc = etree.parse(acrn_config_utilities.SCENARIO_SCHEMA_FILE)
+    xsd_doc = parse(acrn_config_utilities.SCENARIO_SCHEMA_FILE)
     xsd_doc.xinclude()
-    my_schema = xmlschema.XMLSchema11(etree.tostring(xsd_doc, encoding="unicode"))
+    my_schema = xmlschema.XMLSchema11(tostring(xsd_doc, encoding="unicode"))
 
     it = my_schema.iter_errors(scenario_info)
     for idx, validation_error in enumerate(it, start=1):
@@ -124,12 +124,12 @@ def validate_scenario_schema(scenario_info):
             scenario_cfg_lib.ERR_LIST[key] = element + reason
 
 def apply_data_checks(board_info, scenario_info):
-    xsd_doc = etree.parse(acrn_config_utilities.DATACHECK_SCHEMA_FILE)
+    xsd_doc = parse(acrn_config_utilities.DATACHECK_SCHEMA_FILE)
     xsd_doc.xinclude()
-    datachecks_schema = xmlschema.XMLSchema11(etree.tostring(xsd_doc, encoding="unicode"))
+    datachecks_schema = xmlschema.XMLSchema11(tostring(xsd_doc, encoding="unicode"))
 
-    main_etree = etree.parse(board_info)
-    scenario_etree = etree.parse(scenario_info)
+    main_etree = parse(board_info)
+    scenario_etree = parse(scenario_info)
     main_etree.getroot().extend(scenario_etree.getroot()[:])
     # FIXME: Figure out proper error keys for data check failures
     error_key = ""
diff --git a/misc/config_tools/service_vm_config/serial_config.py b/misc/config_tools/service_vm_config/serial_config.py
index cb902f10c..824ecbd20 100644
--- a/misc/config_tools/service_vm_config/serial_config.py
+++ b/misc/config_tools/service_vm_config/serial_config.py
@@ -8,7 +8,7 @@ import sys, os
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'library'))
 
 import argparse
-import lxml.etree
+from defusedxml.lxml import parse
 import acrn_config_utilities
 from acrn_config_utilities import get_node
 
@@ -41,8 +41,8 @@ def main(args):
     Generate serial configuration file for service VM
     :param args: command line args
     """
-    scenario_etree = lxml.etree.parse(args.scenario)
-    allocation_etree = lxml.etree.parse(args.allocation)
+    scenario_etree = parse(args.scenario)
+    allocation_etree = parse(args.allocation)
     vuart_target_vmid = {}
 
     vm_list = scenario_etree.xpath("//vm[load_order = 'SERVICE_VM']")
diff --git a/misc/config_tools/static_allocators/main.py b/misc/config_tools/static_allocators/main.py
index b8732cb31..6163f5170 100755
--- a/misc/config_tools/static_allocators/main.py
+++ b/misc/config_tools/static_allocators/main.py
@@ -7,6 +7,7 @@
 
 import sys, os
 import lxml.etree
+from defusedxml.lxml import parse, fromstring
 import argparse
 sys.path.append(os.path.join(os.path.dirname(os.path.abspath(__file__)), '..', 'library'))
 import acrn_config_utilities
@@ -22,9 +23,9 @@ def main(args):
     scripts_path = os.path.dirname(os.path.realpath(__file__))
     current = os.path.basename(__file__)
 
-    board_etree = lxml.etree.parse(args.board)
-    scenario_etree = lxml.etree.parse(args.scenario)
-    allocation_etree = lxml.etree.ElementTree(element=lxml.etree.fromstring("<acrn-config></acrn-config>"))
+    board_etree = parse(args.board)
+    scenario_etree = parse(args.scenario)
+    allocation_etree = lxml.etree.ElementTree(element=fromstring("<acrn-config></acrn-config>"))
     for script in sorted([f for f in os.listdir(scripts_path) if f.endswith(".py") and f != current]):
         module_name = os.path.splitext(script)[0]
         module = import_module(f"{module_name}")