diff --git a/test/e2e/scheduling/predicates.go b/test/e2e/scheduling/predicates.go
index 3dc801b79d7..2daff177e37 100644
--- a/test/e2e/scheduling/predicates.go
+++ b/test/e2e/scheduling/predicates.go
@@ -718,6 +718,9 @@ var _ = SIGDescribe("SchedulerPredicates [Serial]", func() {
 		topologyKey := "kubernetes.io/e2e-pts-filter"
 
 		ginkgo.BeforeEach(func() {
+			if len(nodeList.Items) < 2 {
+				ginkgo.Skip("At least 2 nodes are required to run the test")
+			}
 			ginkgo.By("Trying to get 2 available nodes which can run pod")
 			nodeNames = Get2NodesThatCanRunPod(f)
 			ginkgo.By(fmt.Sprintf("Apply dedicated topologyKey %v for this test on the 2 nodes.", topologyKey))
diff --git a/test/e2e/scheduling/preemption.go b/test/e2e/scheduling/preemption.go
index 5cf950e9712..9902aad65c4 100644
--- a/test/e2e/scheduling/preemption.go
+++ b/test/e2e/scheduling/preemption.go
@@ -306,6 +306,9 @@ var _ = SIGDescribe("SchedulerPreemption [Serial]", func() {
 		var fakeRes v1.ResourceName = "example.com/fakePTSRes"
 
 		ginkgo.BeforeEach(func() {
+			if len(nodeList.Items) < 2 {
+				ginkgo.Skip("At least 2 nodes are required to run the test")
+			}
 			ginkgo.By("Trying to get 2 available nodes which can run pod")
 			nodeNames = Get2NodesThatCanRunPod(f)
 			ginkgo.By(fmt.Sprintf("Apply dedicated topologyKey %v for this test on the 2 nodes.", topologyKey))
diff --git a/test/e2e/scheduling/priorities.go b/test/e2e/scheduling/priorities.go
index 2c5b0763e31..f7e03a25d4b 100644
--- a/test/e2e/scheduling/priorities.go
+++ b/test/e2e/scheduling/priorities.go
@@ -387,6 +387,9 @@ var _ = SIGDescribe("SchedulerPriorities [Serial]", func() {
 		topologyKey := "kubernetes.io/e2e-pts-score"
 
 		ginkgo.BeforeEach(func() {
+			if len(nodeList.Items) < 2 {
+				ginkgo.Skip("At least 2 nodes are required to run the test")
+			}
 			ginkgo.By("Trying to get 2 available nodes which can run pod")
 			nodeNames = Get2NodesThatCanRunPod(f)
 			ginkgo.By(fmt.Sprintf("Apply dedicated topologyKey %v for this test on the 2 nodes.", topologyKey))