diff --git a/pkg/controller/endpointslice/topologycache/topologycache.go b/pkg/controller/endpointslice/topologycache/topologycache.go
index b9d0c15f73b..a286fd16011 100644
--- a/pkg/controller/endpointslice/topologycache/topologycache.go
+++ b/pkg/controller/endpointslice/topologycache/topologycache.go
@@ -170,9 +170,15 @@ func (t *TopologyCache) SetNodes(nodes []*v1.Node) {
 	totalCPU := resource.Quantity{}
 
 	for _, node := range nodes {
-		if !NodeReady(node.Status) {
+		if hasExcludedLabels(node.Labels) {
+			klog.V(2).Infof("Ignoring node %s because it has an excluded label", node.Name)
 			continue
 		}
+		if !NodeReady(node.Status) {
+			klog.V(2).Infof("Ignoring node %s because it is not ready: %v", node.Name, node.Status.Conditions)
+			continue
+		}
+
 		nodeCPU := node.Status.Allocatable.Cpu()
 		zone, ok := node.Labels[v1.LabelTopologyZone]
 
@@ -254,3 +260,18 @@ func (t *TopologyCache) getAllocations(numEndpoints int) map[string]Allocation {
 
 	return allocations
 }
+
+// Nodes with any of these labels set to any value will be excluded from
+// topology capacity calculations.
+func hasExcludedLabels(labels map[string]string) bool {
+	if len(labels) == 0 {
+		return false
+	}
+	if _, ok := labels["node-role.kubernetes.io/control-plane"]; ok {
+		return true
+	}
+	if _, ok := labels["node-role.kubernetes.io/master"]; ok {
+		return true
+	}
+	return false
+}
diff --git a/pkg/controller/endpointslice/topologycache/topologycache_test.go b/pkg/controller/endpointslice/topologycache/topologycache_test.go
index 6f8bb369a9f..febbdc37a71 100644
--- a/pkg/controller/endpointslice/topologycache/topologycache_test.go
+++ b/pkg/controller/endpointslice/topologycache/topologycache_test.go
@@ -20,7 +20,7 @@ import (
 	"reflect"
 	"testing"
 
-	"k8s.io/api/core/v1"
+	v1 "k8s.io/api/core/v1"
 	discovery "k8s.io/api/discovery/v1"
 	"k8s.io/apimachinery/pkg/api/resource"
 	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
@@ -290,9 +290,10 @@ func TestAddHints(t *testing.T) {
 
 func TestSetNodes(t *testing.T) {
 	type nodeInfo struct {
-		zone  string
-		cpu   resource.Quantity
-		ready v1.ConditionStatus
+		zone   string
+		cpu    resource.Quantity
+		ready  v1.ConditionStatus
+		labels map[string]string
 	}
 
 	testCases := []struct {
@@ -348,6 +349,16 @@ func TestSetNodes(t *testing.T) {
 		expectSufficientNodeInfo: false,
 		expectedCPUByZone:        nil,
 		expectedRatios:           nil,
+	}, {
+		name: "2 zones, control plane node in 1, ready node in 1",
+		nodes: []nodeInfo{
+			{zone: "zone-a", cpu: resource.MustParse("1000m"), ready: v1.ConditionTrue},
+			{zone: "zone-b", cpu: resource.MustParse("1000m"), ready: v1.ConditionTrue,
+				labels: map[string]string{"node-role.kubernetes.io/control-plane": ""}},
+		},
+		expectSufficientNodeInfo: false,
+		expectedCPUByZone:        nil,
+		expectedRatios:           nil,
 	}, {
 		name: "2 zones, unready node in 1, ready node in 2",
 		nodes: []nodeInfo{
@@ -364,6 +375,23 @@ func TestSetNodes(t *testing.T) {
 			"zone-a": 0.5,
 			"zone-b": 0.5,
 		},
+	}, {
+		name: "2 zones, control plane node in 1, ready node in 2",
+		nodes: []nodeInfo{
+			{zone: "zone-a", cpu: resource.MustParse("1000m"), ready: v1.ConditionTrue},
+			{zone: "zone-b", cpu: resource.MustParse("1000m"), ready: v1.ConditionTrue},
+			{zone: "zone-b", cpu: resource.MustParse("1000m"), ready: v1.ConditionTrue,
+				labels: map[string]string{"node-role.kubernetes.io/control-plane": ""}},
+		},
+		expectSufficientNodeInfo: true,
+		expectedCPUByZone: map[string]*resource.Quantity{
+			"zone-a": resource.NewQuantity(1, resource.BinarySI),
+			"zone-b": resource.NewQuantity(1, resource.BinarySI),
+		},
+		expectedRatios: map[string]float64{
+			"zone-a": 0.5,
+			"zone-b": 0.5,
+		},
 	}, {
 		name: "3 zones, 4 nodes in 1, 2 nodes in 1, 1 node in 1",
 		nodes: []nodeInfo{
@@ -393,7 +421,10 @@ func TestSetNodes(t *testing.T) {
 			cache := NewTopologyCache()
 			nodes := make([]*v1.Node, 0, len(tc.nodes))
 			for _, node := range tc.nodes {
-				labels := map[string]string{}
+				labels := node.labels
+				if labels == nil {
+					labels = map[string]string{}
+				}
 				if node.zone != "" {
 					labels[v1.LabelTopologyZone] = node.zone
 				}