diff --git a/libs/core/langchain_core/tools/base.py b/libs/core/langchain_core/tools/base.py
index ff62f3091d4..998490c45df 100644
--- a/libs/core/langchain_core/tools/base.py
+++ b/libs/core/langchain_core/tools/base.py
@@ -934,6 +934,13 @@ def _prep_run_args(
     config = ensure_config(config)
     if _is_tool_call(input):
         tool_call_id: Optional[str] = cast(ToolCall, input)["id"]
+        if not tool_call_id:
+            msg = (
+                "Tool call ID must be a non-empty string. "
+                f"Got '{tool_call_id}' for tool call '{input}'."
+            )
+            raise ValueError(msg)
+
         tool_input: Union[str, dict] = cast(ToolCall, input)["args"].copy()
     else:
         tool_call_id = None
diff --git a/libs/core/tests/unit_tests/test_tools.py b/libs/core/tests/unit_tests/test_tools.py
index afe8c09113a..e7c429a9819 100644
--- a/libs/core/tests/unit_tests/test_tools.py
+++ b/libs/core/tests/unit_tests/test_tools.py
@@ -2457,3 +2457,22 @@ def test_simple_tool_args_schema_dict() -> None:
     assert tool.args == {
         "a": {"title": "A", "type": "integer"},
     }
+
+
+def test_empty_tool_call_id() -> None:
+    @tool
+    def foo(x: int) -> str:
+        """Foo."""
+        return "hi"
+
+    for empty_tool_call_id in (None, ""):
+        with pytest.raises(
+            ValueError,
+            match=(
+                "Tool call ID must be a non-empty string. "
+                f"Got '{empty_tool_call_id}' for tool call '.*'."
+            ),
+        ):
+            foo.invoke(
+                {"type": "tool_call", "args": {"x": 0}, "id": empty_tool_call_id}
+            )